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Discipline "Molecular biology"
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Курсы
Кафедра фундаментальной медицины и биологии
Для обучающихся по специальности "Фармация"
Molecular biology
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Molecular biology
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LECTURE-TYPE CLASSES
Lecture 1. Introduction to molecular biology. Ways of transferring information and energy in living systems
Lecture 2. Nucleic acids: structure and biological functions
Lecture 3. Principles of implementation of genetic information
Lecture 4. Regulation of gene expression in prokaryotes and eukaryotes
Lecutre 5. Post-translational modifications of the protein
Lecture 6. Principles of coordination of metabolic pathways. Regulation of enzymatic activity
Лекция 7. Строение и функции биологических мембран.
Lecture 8. Structure and functions of biological membranes
Lecture 9. The cell life cycle and its regulation
Lecture 10. Cell damage (cell injury)
Lecture 11. Molecular genetic mechanisms of tumor cell transformation and metastasis
SEMINAR-TYPE CLASSES
Т.Б.1.Class 1. Introduction to the molecular biology of the cell. The main classes of biomolecules. Nucleic acids: structure and biological functions.
Т.Б.2.Class 2. Nucleic acids: levels of DNA compactification. DNA replication and repair: mechanisms and biomedical significance. DNA structure damage and repair mechanisms. Medicine that inhibit replication.
Т.Б.3.Class 3. Stages of realization of genetic information. Structure and functions of various types of RNA. Molecular mechanisms of transcription and translation. Part 1, 2.
Т.Б.4.Class 4. Regulation of gene expression in prokaryotes. The theory of the "operon". Mechanisms of gene induction and repression in eukaryotes. Medicines that modulate gene expression. Part 1, 2.
Т.Б.5.Class 5. Molecular genetic technologies in the development and study of medicines. Prospects of gene therapy in the treatment of diseases. Part 1, 2.
Т.Б.6. Final lesson for training module No. 1: “Structure and functions of nucleic acids. Peculiarities of regulation of gene expression in prokaryotes and eukaryotes.” Part 1.2
Class 7. Classification and functions of proteins. Methods of studying the structure of proteins. The use of enzymes in molecular genetic research
Class 8. Post-translational modifications of the protein. Protein folding and its disorders. Molecular mechanisms of proteinopathies. Proteins and enzymes as biomarkers
Class 9. Principles of coordination of metabolic pathways. Regulation of enzymatic activity. Proteins and enzymes as targets for drugs
Class 10. Structure and functions of biological membranes. Membrane proteins. Mechanisms of transport of substances through the membrane. Intercellular contacts
Т.Б.11. Class 11. The receptor function of biological membranes. Principles of receptor signal transmission. Metabotropic and ionotropic receptors.
Т.Б.12. Class 12. Catalytic receptors. Molecular mechanisms of signal transduction from nuclear and cytoplasmic receptors. Regulation of receptor activity
Т.Б.13. Final lesson for training module No. 2: “Regulation of enzyme activity. Biological membranes. Receptor signal transduction." Part 1.2
Т.Б.14. Cell cycle and its regulation. Phases of mitosis. Proteins and enzymes in the regulation of cell proliferation. Growth factors. Part 1.2
Т.Б.15. Cell damage. Pathobiochemical aspects of necrosis. Types of programmed cell death. The role of apoptosis in normal and pathological conditions. Part 1.2
Т.Б.16. Molecular genetic mechanisms of tumor cell transformation and metastasis. Principles of development and study of antitumor drugs. Part 1.2
Т.Б.17. Final lesson for training module No. 3: “Regulation of cell proliferative activity. Mechanisms of cell death. Oncogenesis". Part 1, 2
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