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Discipline "Molecular biology"
В начало
Курсы
Кафедра фундаментальной медицины и биологии
Для обучающихся по специальности "Фармация"
Molecular biology
Т.Б.16. Molecular genetic mechanisms of tumor cell transformation and metastasis. Principles of development and study of antitumor drugs. Part 1.2
Molecular mechanisms of tumor transformation
Molecular mechanisms of tumor transformation
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◄ Class 16. Study Guide
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The discipline is not implemented in the spring semester of the 2023-2024 academic year.
Schedule of classes, training and consultations
Plans for thematic lessons of lecture type, seminar type and independent work.
Calendar-thematic lesson plans for the autumn semester 2023-2024 academic year
Seminar-type classes 208 Pharm (2 in.p.)
Seminar-type classes 209 Pharm (2 in.p.)
Individual consultations and training
Individual consultations and training
Lecture 1 - Introduction to molecular biology. Ways of transferring information and energy in living systems
Lecture 2 - Nucleic acids: structure and biological functions
Lecture 3 - Principles of implementation of genetic information
Lecture 4 - Regulation of gene expression in prokaryotes and eukaryotes
Lecture 5 - Post-translational modifications of the protein
Lecture 6 - Principles of coordination of metabolic pathways
Lecture 7 - Structure and functions of biological membranes
Lecture 8 - Receptor function of biological membranes
Lecture 9 - The cell life cycle and its regulation
Lecture 10 - Cell damage
Lecture 11 - Mechanisms of tumor cell transformation
Study Guide for ALL classes
Recommended reading
How to study in medical school
Videos
Biology course
Class 1. Study Guide
Molecular cell biology
Class 2. Study Guide
DNA replication (video)
DNA replication
Class 3. Study Guide
Genetic code table
Транскрипция
Трансляция
https://Transcription-Translation-and-Replication
Class 4. Study Guide
Gene Regulation and the Order of the Operon
Class 5. Study Guide
Gene therapy (Video)
How Is Insulin Made By Biotechnology
Production of antibiotics
The list of questions
Class 7. Study Guide
Introduction to proteins and amino acids
Orders of protein structure
Protein structure
Class 8. Study Guide
Proteinopathies. Prions
Conformational stability: Protein folding and denaturation
Class 9. Study Guide
Allosteric enzymes
What is ATP?
Coordination of metabolic pathways
Class 10. Study Guide
Structure of biological membranes
Plasma membranes
Receptor function of membranes
Class 11. Study Guide
Receptors: Types & Functions
Intro to Cell Signaling
G Protein Coupled Receptors
Types of Receptors
Ionotropic and Metabotropic Receptors
Drug–Receptor Interactions
Class 12. Study Guide
Intracellular Signaling / Second Messenger System
The Insulin Signaling Pathway
Insulin Signal Transduction Pathway
Enzyme Linked Receptors
The list of questions
Class 14. Study Guide
Cell Cycle Regulation
Unit: Cell division
Cell cycle control
Class 15. Study Guide
Cell Injury and Cell Death. Causes, mechanism and different types of cell injury
Apoptosis (Programmed Cell Death)
What is Necrosis vs What is Apoptosis?
Class 16. Study Guide
Cancer and the cell cycle
The list of questions
Schedule of tests/exams/tests with assessment/pre-examination consultations/retakes
Assessment tools for certification and the procedure for certification of students
Порядок проведения промежуточной аттестации обучающихся, в том числе с применением дистанционных образовательных технологий на кафедре фундаментальной медицины и биологии ФГБОУ ВО ВолгГМУ Минздрава России
The list of questions for EXAM
CRITERIA FOR ASSESSING STUDENTS' KNOWLEDGE
Pre-Exam Test for students (Перечень вопросов для 1 этапа экзамена (тестовый контроль))
Cancer and the cell cycle ►
Molecular biology
Общее
Schedule of classes, training and consultations
Methodological and other documents developed to support the educational process
Recording presence in classes
Individual consultations and training
LECTURE-TYPE CLASSES
Lecture 1. Introduction to molecular biology. Ways of transferring information and energy in living systems
Lecture 2. Nucleic acids: structure and biological functions
Lecture 3. Principles of implementation of genetic information
Lecture 4. Regulation of gene expression in prokaryotes and eukaryotes
Lecutre 5. Post-translational modifications of the protein
Lecture 6. Principles of coordination of metabolic pathways. Regulation of enzymatic activity
Лекция 7. Строение и функции биологических мембран.
Lecture 8. Structure and functions of biological membranes
Lecture 9. The cell life cycle and its regulation
Lecture 10. Cell damage (cell injury)
Lecture 11. Molecular genetic mechanisms of tumor cell transformation and metastasis
SEMINAR-TYPE CLASSES
Т.Б.1.Class 1. Introduction to the molecular biology of the cell. The main classes of biomolecules. Nucleic acids: structure and biological functions.
Т.Б.2.Class 2. Nucleic acids: levels of DNA compactification. DNA replication and repair: mechanisms and biomedical significance. DNA structure damage and repair mechanisms. Medicine that inhibit replication.
Т.Б.3.Class 3. Stages of realization of genetic information. Structure and functions of various types of RNA. Molecular mechanisms of transcription and translation. Part 1, 2.
Т.Б.4.Class 4. Regulation of gene expression in prokaryotes. The theory of the "operon". Mechanisms of gene induction and repression in eukaryotes. Medicines that modulate gene expression. Part 1, 2.
Т.Б.5.Class 5. Molecular genetic technologies in the development and study of medicines. Prospects of gene therapy in the treatment of diseases. Part 1, 2.
Т.Б.6. Final lesson for training module No. 1: “Structure and functions of nucleic acids. Peculiarities of regulation of gene expression in prokaryotes and eukaryotes.” Part 1.2
Class 7. Classification and functions of proteins. Methods of studying the structure of proteins. The use of enzymes in molecular genetic research
Class 8. Post-translational modifications of the protein. Protein folding and its disorders. Molecular mechanisms of proteinopathies. Proteins and enzymes as biomarkers
Class 9. Principles of coordination of metabolic pathways. Regulation of enzymatic activity. Proteins and enzymes as targets for drugs
Class 10. Structure and functions of biological membranes. Membrane proteins. Mechanisms of transport of substances through the membrane. Intercellular contacts
Т.Б.11. Class 11. The receptor function of biological membranes. Principles of receptor signal transmission. Metabotropic and ionotropic receptors.
Т.Б.12. Class 12. Catalytic receptors. Molecular mechanisms of signal transduction from nuclear and cytoplasmic receptors. Regulation of receptor activity
Т.Б.13. Final lesson for training module No. 2: “Regulation of enzyme activity. Biological membranes. Receptor signal transduction." Part 1.2
Т.Б.14. Cell cycle and its regulation. Phases of mitosis. Proteins and enzymes in the regulation of cell proliferation. Growth factors. Part 1.2
Т.Б.15. Cell damage. Pathobiochemical aspects of necrosis. Types of programmed cell death. The role of apoptosis in normal and pathological conditions. Part 1.2
Т.Б.16. Molecular genetic mechanisms of tumor cell transformation and metastasis. Principles of development and study of antitumor drugs. Part 1.2
Т.Б.17. Final lesson for training module No. 3: “Regulation of cell proliferative activity. Mechanisms of cell death. Oncogenesis". Part 1, 2
Student's independent work
Assessment tools for ongoing assessment
Schedules of tests, exams, consultations, retakes
INTERMEDIATE CERTIFICATION
Assessment of student satisfaction
В начало
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