Discipline "Molecular biology"

Stages of realization of genetic information. Structure and functions of various types of RNA. Molecular mechanisms of transcription and translation. Part 1, 2.

Study questions:

1. Stages of implementation of genetic information. The concept of transcription and translation
2. The main types of RNA and their functions. Types of RNA polymerases
3. RNA biosynthesis: stages of the process. Features of transcription in eukaryotes.
4. Post-transcriptional changes in RNA. Alternative splicing
5. Protein biosynthesis. The genetic code and its properties. Function and structural features of tRNA
6. Activation of amino acids
7. Ribosomes: structural features in prokaryotes and eukaryotes. Active centers of ribosomes
8. Polyribosomes.

Vocabulary (list of mandatory terms and concepts):

• transcription;
• RNA polymerase;
• transcription factors;
• promoter;
• terminator;
• polyadenylation;
• ribozymes;
• cistron;
• exons;
• introns;
• spliceosome;
• alternative splicing;